Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

G2-checkpoint abrogation in irradiated lymphocytes: A new cytogenetic approach to assess individual radiosensitivity and predisposition to cancer.

International journal of oncology - 1 Nov 2009

Terzoudi Georgia I, Hatzi Vasiliki I, Barszczewska Katarzyna, Manola Kalliopi N, Stavropoulou Chryssa, Angelakis Philip, Pantelias Gabriel E

Abstract excerpt

Increased yield of chromatid breaks, following in vitro G2-phase lymphocyte irradiation, can be a marker of individual radiosensitivity and cancer predisposing genes whose role is to respond to DNA damage. Mutations or polymorphisms of genes encoding DNA repair pathways may underlie the increased chromosomal radiosensitivity. However, genes that facilitate DNA damage recognition, using signal transduction...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Damage
Share to G2 Phase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Techniques

Share to Hematologic Tests

Share to Lymphocytes

Share to Neoplasms

Share to Radiation Tolerance

Share to Reproducibility of Results

Source

Identifiers

PMID: 19787278
DOI: 10.3892/ijo_00000439

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

G2-checkpoint abrogation in irradiated lymphocytes: A new cytogenetic approach to assess individual radiosensitivity and predisposition to cancer.PMID 19787278Read ↗

Polymorphisms in double strand break repair related genes influence radiosensitivity phenotype in lymphocytes from healthy individuals.Semantic proximity Read ↗

Genetic determination of chromosomal radiosensitivities in G0- and G2-phase human lymphocytes.Semantic proximity Read ↗

Lymphocyte radiosensitivity in BRCA1 and BRCA2 mutation carriers and implications for breast cancer susceptibility.Semantic proximity Read ↗

Differential DNA Damage Response of Peripheral Blood Lymphocyte Populations.Semantic proximity Read ↗

A standardized G2-assay for the prediction of individual radiosensitivitySemantic proximity Read ↗

In vivo versus in vitro individual radiosensitivity analysed in healthy donors and in prostate cancer patients with and without severe side effects after radiotherapySemantic proximity Read ↗

Human Radiosensitivity and Radiosusceptibility: What Are the Differences?Semantic proximity Read ↗

[Individual response to ionising radiation: What predictive assay(s) to choose?].Semantic proximity Read ↗

Analysis of chromosomal radiosensitivity of healthy BRCA2 mutation carriers and non-carriers in BRCA families with the G2 micronucleus assay.Semantic proximity Read ↗

Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants.Semantic proximity Read ↗

Evaluation of Different Biomarkers to Predict Individual Radiosensitivity in an Inter-Laboratory Comparison–Lessons for Future StudiesSemantic proximity Read ↗

Gender bias in individual radiosensitivity and the association with genetic polymorphic variations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.