Article
The C-509T promoter polymorphism of the transforming growth factor beta-1 gene is associated with levels of total and specific IgE in a Colombian population.
International archives of allergy and immunology - 1 Jan 2010
Acevedo Nathalie, Vergara Candelaria, Gusmão Leonor, Jiménez Silvia, Martínez Beatriz, Mercado Dilia, Caraballo Luis
Abstract excerpt
BACKGROUND: The C-509T polymorphism of the transforming growth factor beta-1 (TGFB1) gene has been associated with asthma and asthma-related phenotypes, but its influence on total and specific IgE levels is controversial. OBJECTIVE: To investigate the association between C-509T and asthma, as well as total IgE and specific IgE against Blomia tropicalis and Dermatophagoides pteronyssinus, in a Colombian...
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