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Gene promoter methylation assayed in exhaled breath, with differences in smokers and lung cancer patients

25 Sept 2009

Abstract excerpt

BACKGROUND: There is a need for new, noninvasive risk assessment tools for use in lung cancer population screening and prevention programs. METHODS: To investigate the technical feasibility of determining DNA methylation in exhaled breath condensate, we applied our previously-developed method for tag-adapted bisulfite genomic DNA sequencing (tBGS) for mapping of DNA methylation, and adapted it to exhaled breath...

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Share to Chronic Obstructive Pulmonary Disease (COPD) Research
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PMID: 19781081
DOI: 10.1186/1465-9921-10-86

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