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Article

Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation.

The Journal of biological chemistry - 9 Sept 2005

Onodera Jun, Ohsumi Yoshinori

Abstract excerpt

Autophagy is a transport system of cytoplasmic components to the lysosome/vacuole for degradation well conserved in eukaryotes. Autophagy is strongly induced by nutrient starvation. Several specific proteins, including amino acid synthesis enzymes and vacuolar enzymes, are increased during nitrogen starvation in wild-type cells but not in autophagy-defective delta atg7 cells despite similar mRNA levels. We...

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Identifiers

PMID: 16027116
DOI: 10.1074/jbc.M506736200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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