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Article

Expression of the HFE allelic variant H63D in SH-SY5Y cells affects tau phosphorylation at serine residues.

Neurobiology of aging - 1 Aug 2011

Hall Eric C, Lee Sang Y, Mairuae Nootchanat, Simmons Zachary, Connor James R

Abstract excerpt

A number of genetic association studies have appeared that address HFE gene variants in neurodegenerative disorders. However, the cellular impact of HFE in the nervous system has received little attention. To begin to address the role of the HFE allelic variants on cellular events associated with neurodegeneration, we examined the hypothesis that HFE polymorphisms are associated with alterations in tau...

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Source

Identifiers

PMID: 19775775
DOI: 10.1016/j.neurobiolaging.2009.08.012

Genes

HFE

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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