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Article

Autologous bone marrow mononuclear cells enhance recovery after acute ischemic stroke in young and middle-aged rats.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Jan 2010

Brenneman Miranda, Sharma Sushil, Harting Matthew, Strong Roger, Cox Charles S, Aronowski Jarek, Grotta James C, Savitz Sean I

Abstract excerpt

We investigated intra-arterially administered autologous bone marrow mononuclear cells (MNCs) in rats with acute ischemic stroke. Long Evans rats (2 to 3 months or 12 months old) underwent tandem reversible common carotid artery (CCA)/middle cerebral artery (MCA) occlusion (CCAo/MCAo) for 3 h and then 24 h later underwent tibial bone marrow harvest. Ten million or 4 million cells were re-injected by an...

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Identifiers

PMID: 19773802
DOI: 10.1038/jcbfm.2009.198
PMCID: PMC2893568

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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