Article
Mesenchymal stem cells derived from peripheral blood protects against ischemia.
Journal of neurotrauma - 1 Mar 2007
Ukai Ryo, Honmou Osamu, Harada Kuniaki, Houkin Kiyohiro, Hamada Hirofumi, Kocsis Jeffery D
Abstract excerpt
Intravenous delivery of mesenchymal stem cells (MSCs) prepared from bone marrow (BMSCs) reduces infarction volume and ameliorates functional deficits in a rat cerebral ischemia model. MSC-like multipotent precursor cells (PMSCs) have also been suggested to exist in peripheral blood. To test the hypothesis that treatment with PMSCs may have a therapeutic benefit in stroke, we compared the efficacy of systemic...
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