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Article

The Use of microRNAs to Modulate Redox and Immune Response to Stroke

20 Dec 2013

Abstract excerpt

SIGNIFICANCE: Cerebral ischemia is a major cause of death and disability throughout the world, yet therapeutic options remain limited. The interplay between the cellular redox state and the immune response plays a critical role in determining the extent of neural cell injury after ischemia and reperfusion. Excessive amounts of reactive oxygen species (ROS) generated by mitochondria and other sources act both as...

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PMID: 24359188
DOI: 10.1089/ars.2013.5757

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