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Article

A human D1 dopamine receptor gene is located on chromosome 5 at q35.1 and identifies an EcoRI RFLP.

American journal of human genetics - 1 Nov 1990

Grandy D K, Zhou Q Y, Allen L, Litt R, Magenis R E, Civelli O, Litt M

Abstract excerpt

Dopaminergic neurons have been shown to affect voluntary movement, hormone secretion, and emotional tone. Mediating these activities are two receptor subtypes, D1 and D2, which are biochemically and pharmacologically distinct. The D1 subtype, the most abundant form of dopamine receptor in the central nervous system, stimulates adenylate cyclase, modulates D2 receptor activity, regulates neuron growth and...

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Topics

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Share to Alleles
Share to Chromosome Mapping
Share to Chromosomes, Human, Pair 5

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cloning, Molecular

Share to Deoxyribonuclease EcoRI

Share to Genetic Linkage

Share to Polymorphism, Restriction Fragment Length

Share to Receptors, Dopamine

Source

Open in PubMed Open full text

Identifiers

PMID: 1977312
PMCID: PMC1683700

Genes

DRD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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