Article
A human D1 dopamine receptor gene is located on chromosome 5 at q35.1 and identifies an EcoRI RFLP.
American journal of human genetics - 1 Nov 1990
Grandy D K, Zhou Q Y, Allen L, Litt R, Magenis R E, Civelli O, Litt M
Abstract excerpt
Dopaminergic neurons have been shown to affect voluntary movement, hormone secretion, and emotional tone. Mediating these activities are two receptor subtypes, D1 and D2, which are biochemically and pharmacologically distinct. The D1 subtype, the most abundant form of dopamine receptor in the cen...
Topics
- Alleles
- Chromosome Mapping
- Chromosomes, Human, Pair 5
- Cloning, Molecular
- Deoxyribonuclease EcoRI
- Genetic Linkage
- Humans
- Male
- Polymorphism, Restriction Fragment Length
- Receptors, Dopamine
- Receptors, Dopamine D1