Possible locus for bipolar disorder near the dopamine transporter on chromosome 5.

doi:10.1002/(SICI)1096-8628(19961122)67:6<533::AID-AJMG4>3.0.CO;2-I

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Article

Possible locus for bipolar disorder near the dopamine transporter on chromosome 5.

American journal of medical genetics - 22 Nov 1996

Kelsoe J R, Sadovnick A D, Kristbjarnarson H, Bergesch P, Mroczkowski-Parker Z, Drennan M, Rapaport M H, Flodman P, Spence M A, Remick R A

Abstract excerpt

The dopamine transporter (DAT) plays a key role in the regulation of dopaminergic neurotransmission by mediating the active reuptake of synaptic dopamine. It is an important candidate gene for bipolar disorder because of data implicating dopamine abnormalities in mania, and because it is the site...

Topics

Bipolar Disorder
Carrier Proteins
Chromosomes, Human, Pair 5
Dopamine
Dopamine Plasma Membrane Transport Proteins
Genotype
Humans
Membrane Glycoproteins
Membrane Transport Proteins
Nerve Tissue Proteins
Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 8950410
DOI: 10.1002/(SICI)1096-8628(19961122)67:6<533::AID-AJMG4>3.0.CO;2-I

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8950410-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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