Article
Two-stage case-control association study of dopamine-related genes and migraine.
BMC medical genetics - 21 Sept 2009
Corominas Roser, Ribases Marta, Camiña Montserrat, Cuenca-León Ester, Pardo Julio, Boronat Susana, Sobrido María-Jesús, Cormand Bru, Macaya Alfons
Abstract excerpt
BACKGROUND: We previously reported risk haplotypes for two genes related with serotonin and dopamine metabolism: MAOA in migraine without aura and DDC in migraine with aura. Herein we investigate the contribution to migraine susceptibility of eight additional genes involved in dopamine neurotransmission. METHODS: We performed a two-stage case-control association study of 50 tag single nucleotide polymorphisms...
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