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Article

Genotyping and mapping assay of single-nucleotide polymorphisms in CYP3A5 using DNA-binding zinc(II) complexes.

Clinical biochemistry - 1 Feb 2010

Kinoshita Eiji, Kinoshita-Kikuta Emiko, Nakashima Hiromi, Koike Tohru

Abstract excerpt

OBJECTIVE: It is clinically important to detect the single-nucleotide polymorphism (SNP) of CYP3A53 (6986A>G) associated with enzymatic activity for drug metabolism. The aim of this study was to establish an accurate strategy for SNP screening. DESIGN AND METHODS: Polyacrylamide gel electrophoresis (PAGE) using zinc(II) complexes were applied for SNP detection. Genomic analyses of 19 healthy subjects were...

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PMID: 19769955
DOI: 10.1016/j.clinbiochem.2009.09.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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