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Article

Ocular prostaglandin production and morphology in mice lacking a single isoform of cyclooxygenase.

Prostaglandins, leukotrienes, and essential fatty acids - 1 Jan 2000

Cryan Lorna M, Fitzgerald Desmond J, O'Brien Colm

Abstract excerpt

Prostaglandins have many important roles in ocular physiology and are used clinically for the treatment of glaucoma. The aim of this study was to analyse the contribution of each cyclooxygenase isoform to ocular prostaglandin production using isoform-specific knockout mice. Ex vivo PGE(2), 6-keto-PGF(1alpha), and TXB(2) production was measured from whole eyes, corneal tissue, uveoscleral tissue, lens, retina and...

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Identifiers

PMID: 19767186
DOI: 10.1016/j.plefa.2009.08.001

Genes

PGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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