Article
Intercrossing of phage genomes in a phage cocktail and stable coexistence with Escherichia coli O157:H7 in anaerobic continuous culture.
Applied microbiology and biotechnology - 1 Feb 2010
Kunisaki Hiroya, Tanji Yasunori
Abstract excerpt
The emergence of phage-resistant cells is the most serious problem for realizing phage therapy and is observed frequently if only one phage strain is used against a particular bacterium. By contrast, using multiple phages (phage cocktail) can delay or control the appearance of phage-resistant cel...
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