Article
Coevolution of bacteriophage PP01 and Escherichia coli O157:H7 in continuous culture.
Applied and environmental microbiology - 1 Jan 2003
Mizoguchi Katsunori, Morita Masatomo, Fischer Curt R, Yoichi Masatoshi, Tanji Yasunori, Unno Hajime
Abstract excerpt
The interaction between Escherichia coli O157:H7 and its specific bacteriophage PP01 was investigated in chemostat continuous culture. Following the addition of bacteriophage PP01, E. coli O157:H7 cell lysis was observed by over 4 orders of magnitude at a dilution rate of 0.876 h(-1) and by 3 orders of magnitude at a lower dilution rate (0.327 h(-1)). However, the appearance of a series of phage-resistant E. coli...
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