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The co-localizing Zorya II, Druantia III, and ARMADA II defense systems on O-island 172 confer synergistic anti-phage defense in enterohemorrhagic <i>Escherichia coli</i>

2025-09-24

Abstract excerpt

<h4>SUMMARY</h4> In this study, we show that the enterohemorrhagic Escherichia coli (EHEC) strain EDL933 Δ stx1/2 is highly resistant to phages. The genes encoding the three phage defense systems Zorya II, Druantia III, and ARMADA II were found to co-localize on O-island 172 (OI-172) in EDL933. The three phage defense systems co-occur in 426 E. coli strains comprising 66 distinct serotypes, including 277 O157:...

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Identifiers and source

Literature Corpus work
9e38f136-bddf-5cbe-b61b-5485ef90b568
DOI
10.1101/2025.09.22.677730
Open publication

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