Article
Gene expression profiling in cells with enhanced gamma-secretase activity.
PloS one - 18 Sept 2009
Magold Alexandra I, Cacquevel Matthias, Fraering Patrick C
Abstract excerpt
BACKGROUND: Processing by gamma-secretase of many type-I membrane protein substrates triggers signaling cascades by releasing intracellular domains (ICDs) that, following nuclear translocation, modulate the transcription of different genes regulating a diverse array of cellular and biological pro...
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