Article
Estimating the retrotransposition rate of human Alu elements.
Gene - 24 May 2006
Cordaux Richard, Hedges Dale J, Herke Scott W, Batzer Mark A
Abstract excerpt
Mobile elements such as Alu repeats have substantially altered the architecture of the human genome, and de novo mobile element insertions sometimes cause genetic disorders. Previous estimates for the retrotransposition rate (RR) of Alu elements in humans of one new insertion every approximately 100-125 births were developed prior to the sequencing of the human and chimpanzee genomes. Here, we used two...
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