Article
Characterization of fHbp, nhba (gna2132), nadA, porA, sequence type (ST), and genomic presence of IS1301 in group B meningococcal ST269 clonal complex isolates from England and Wales.
Journal of clinical microbiology - 1 Nov 2009
Lucidarme Jay, Comanducci Maurizio, Findlow Jamie, Gray Stephen J, Kaczmarski Edward B, Guiver Malcolm, Kugelberg Elisabeth, Vallely Pamela J, Oster Philipp, Pizza Mariagrazia, Bambini Stefania, Muzzi Alessandro, Tang Christoph M, Borrow Ray
Abstract excerpt
Highly effective glycoconjugate vaccines exist against four of the five major pathogenic groups of meningococci: A, C, W-135, and Y. An equivalent vaccine against group B meningococci (menB) has remained elusive due to the poorly immunogenic capsular polysaccharide. A promising alternative, the investigational recombinant menB (rMenB)- outer membrane vesicle (OMV) vaccine, contains fHBP, NHBA (previously...
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