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Article

Bioinformatic analysis of meningococcal Msf and Opc to inform vaccine antigen design.

PloS one - 1 Jan 2018

Andreae Clio A, Sessions Richard B, Virji Mumtaz, Hill Darryl J

Abstract excerpt

Neisseria meningitidis is an antigenically and genetically variable Gram-negative bacterium and a causative agent of meningococcal meningitis and septicaemia. Meningococci encode many outer membrane proteins, including Opa, Opc, Msf, fHbp and NadA, identified as being involved in colonisation of the host and evasion of the immune response. Although vaccines are available for the prevention of some types of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29547646
DOI: 10.1371/journal.pone.0193940
PMCID: PMC5856348

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