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Article

MDM2 SNP309 associates with accelerated pancreatic adenocarcinoma formation.

Pancreas - 1 Jan 2010

Grochola Lukasz F, Müller Thomas H, Bond Gareth L, Taubert Helge, Udelnow Andrej, Würl Peter

Abstract excerpt

OBJECTIVES: The G-allele of a single nucleotide polymorphism in the promoter of the MDM2 gene (MDM2 SNP309, T/G) associates with the acceleration of tumor formation and an increased risk for developing various malignancies. In this report, the possible role of the MDM2 SNP309 locus with regard to sex, age, and p53 mutational status in the development and progression of pancreatic ductal adenocarcinoma (PDAC) was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19752772
DOI: 10.1097/MPA.0b013e3181b9f105

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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