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Article

Genetic association between monoamine oxidase A microsatellite and RFLP alleles and bipolar affective disorder: analysis and meta-analysis.

Human molecular genetics - 1 Jun 1996

Rubinsztein D C, Leggo J, Goodburn S, Walsh C, Jain S, Paykel E S

Abstract excerpt

The monoamine oxidase A locus (MAOA) at Xp11 was considered a good candidate to investigate in bipolar affective disorder since this enzyme plays an important role in the degradation of various neurotransmitters and a mutation in this gene has been associated with borderline mental retardation and a behavioural phenotype that has some resemblance to the manic syndrome. Previous association studies comparing...

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Source

Identifiers

PMID: 8776592
DOI: 10.1093/hmg/5.6.779

Genes

MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic association between monoamine oxidase A microsatellite and RFLP alleles and bipolar affective disorder: analysis and meta-analysis.PMID 8776592Read ↗

Analysis of the monoamine oxidase A (MAOA) gene in bipolar affective disorder by association studies, meta-analyses, and sequencing of the promoterSemantic proximity Read ↗

Genetic association between monoamine oxidase and manic-depressive illness: comparison of relative risk and haplotype relative risk data.Semantic proximity Read ↗

No evidence for allelic association between bipolar disorder and monoamine oxidase A gene polymorphisms.Semantic proximity Read ↗

Association between bipolar disorder and monoamine oxidase A gene polymorphisms: results of a multicenter study.Semantic proximity Read ↗

Evidence for a genetic association between alleles of monoamine oxidase A gene and bipolar affective disorder.Semantic proximity Read ↗

MAOA Variants and Genetic Susceptibility to Major Psychiatric Disorders.Semantic proximity Read ↗

Association analysis between mood disorder and monoamine oxidase gene.Semantic proximity Read ↗

The monoamine oxidase-A gene and major psychosis in Japanese subjects.Semantic proximity Read ↗

Meta-analysis of the association between the monoamine oxidase-A gene and mood disorders.Semantic proximity Read ↗

Association between a functional polymorphism in the monoamine oxidase A gene promoter and major depressive disorder.Semantic proximity Read ↗

Neither single-marker nor haplotype analyses support an association between monoamine oxidase A gene and bipolar disorder.Semantic proximity Read ↗

Association between the serotonin 2A receptor gene and bipolar affective disorder in an Australian cohort.Semantic proximity Read ↗

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