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ABC drug transporters and immunity: novel therapeutic targets in autoimmunity and cancer

10 Sept 2009

Abstract excerpt

ABC transporters were identified originally for their contribution to clinical MDR as a result of their capacity to extrude various unrelated cytotoxic drugs. More recent reports have shown that ABC transporters can play important roles in the development, differentiation, and maturation of immune cells and are involved in migration of immune effector cells to sites of inflammation. Many of the currently...

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PMID: 19745159
DOI: 10.1189/jlb.0309147

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