Article
Association of osteoarthritis with homozygosity for a 5.8 kb Taq I fragment of the alpha 1-antichymotrypsin gene.
British journal of rheumatology - 1 Aug 1990
Sakkas L I, Macfarlane D G, Bird H, Welsh K I, Panayi G S
Abstract excerpt
The genes coding for the protease inhibitors alpha 1-antitrypsin (A1AT) and alpha 1-antichymotrypsin (A1ACT) were analysed by Southern blot in patients with rheumatoid arthritis, psoriatic arthritis, psoriasis without arthritis, polymyalgia rheumatica and generalized osteoarthritis. The probe/res...
Topics
- Alleles
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Gene Frequency
- Homozygote
- Humans
- Osteoarthritis
- Peptide Fragments
- Polymorphism, Restriction Fragment Length
- Polymyalgia Rheumatica
- Psoriasis
- alpha 1-Antichymotrypsin
- alpha 1-Antitrypsin