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Article

Is Apoptosis the Cause of Noninsertional Achilles Tendinopathy?

9 Sept 2009

Abstract excerpt

BACKGROUND: The pathogenesis of chronic tendinopathy is unclear but it does not appear to be an inflammatory process. Apoptosis may lead to degenerate tissue through a nitric oxide-mediated pathway. Increased levels of nitric oxide have been demonstrated in Achilles tendinopathy. HYPOTHESIS: Nitric oxide-mediated apoptosis is an important mechanism in the development of Achilles tendinopathy. STUDY DESIGN:...

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PMID: 19741110
DOI: 10.1177/0363546509340264

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