Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of gene expression in human tendinopathy.

BMC musculoskeletal disorders - 3 May 2011

Jelinsky Scott A, Rodeo Scott A, Li Jian, Gulotta Lawrence V, Archambault Joanne M, Seeherman Howard J

Abstract excerpt

BACKGROUND: Chronic tendon injuries, also known as tendinopathies, are common among professional and recreational athletes. These injuries result in a significant amount of morbidity and health care expenditure, yet little is known about the molecular mechanisms leading to tendinopathy. METHODS: We have used histological evaluation and molecular profiling to determine gene expression changes in 23 human patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Chronic Disease
Share to Extracellular Matrix Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Genetic Predisposition to Disease

Share to Shoulder Injury and Treatment

Share to Tendon Structure and Treatment

Share to Tendons

Source

Open in PubMed Open full text

Identifiers

PMID: 21539748
DOI: 10.1186/1471-2474-12-86
PMCID: PMC3095578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of gene expression in human tendinopathy.PMID 21539748Read ↗

Lessons we can learn from gene expression patterns in rotator cuff tears and tendinopathies.Semantic proximity Read ↗

Gene expression and matrix turnover in overused and damaged tendonsSemantic proximity Read ↗

Multiple changes in gene expression in chronic human Achilles tendinopathySemantic proximity Read ↗

The role of stromal-immune cell interactions in the pathogenesis of tendinopathySemantic proximity Read ↗

Single-cell and spatial transcriptomics reveal changes in cell heterogeneity during progression of human tendinopathySemantic proximity Read ↗

Conjoint analysis of lncRNA and mRNA expression in rotator cuff tendinopathySemantic proximity Read ↗

Screening of key biomarkers of tendinopathy based on bioinformatics and machine learning algorithmsSemantic proximity Read ↗

Targeting the NF-κB signaling pathway in chronic tendon diseaseSemantic proximity Read ↗

Widespread diversity in the transcriptomes of functionally divergent limb tendonsSemantic proximity Read ↗

Overexpression of mechanical sensitive miR-337-3p alleviates ectopic ossification in rat tendinopathy model via targeting IRS1 and Nox4 of tendon-derived stem cellsSemantic proximity Read ↗

Single-cell transcriptomic profiling reveals distinct mechanical responses between normal and diseased tendon progenitor cellsSemantic proximity Read ↗

Multi-omic single cell analysis resolves novel stromal cell populations in healthy and diseased human tendonSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.