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Article

The Impact of Transgenic Mosquitoes on Dengue Virulence to Humans and Mosquitoes

8 Sept 2009

Abstract excerpt

Dengue is a major public health concern in the tropics and subtropics. Innovative transgenic strategies to render Aedes aegypti mosquitoes, the primary vector of dengue, incompetent for dengue transmission are under development. We modeled the evolutionary impact of different transgenic mosquito strategies on dengue-induced mortality, that is, dengue virulence, to both humans and mosquitoes. This model...

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PMID: 19737112
DOI: 10.1086/605403

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