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Article

A reduce and replace strategy for suppressing vector-borne diseases: insights from a stochastic, spatial model.

PloS one - 1 Jan 2013

Okamoto Kenichi W, Robert Michael A, Lloyd Alun L, Gould Fred

Abstract excerpt

Two basic strategies have been proposed for using transgenic Aedes aegypti mosquitoes to decrease dengue virus transmission: population reduction and population replacement. Here we model releases of a strain of Ae. aegypti carrying both a gene causing conditional adult female mortality and a gene blocking virus transmission into a wild population to assess whether such releases could reduce the number of...

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Identifiers

PMID: 24376506
DOI: 10.1371/journal.pone.0081860
PMCID: PMC3869666

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