Article
Beta-adrenoceptor metabolism in wild-type, Gs, and protein kinase A-variant S49 cells.
The American journal of physiology - 1 Jul 1990
Jasper J R, Motulsky H J, Mahan L C, Insel P A
Abstract excerpt
To determine the role of the stimulatory guanine nucleotide-binding protein, Gs, and adenosine 3',5'-cyclic monophosphate (cAMP)-dependent protein kinase in the basal metabolism of beta-adrenergic receptors in S49 lymphoma cells, we measured the return of receptor number and function after irreve...
Topics
- Adrenergic beta-Antagonists
- Animals
- Binding, Competitive
- Cell Line
- Clone Cells
- Cyclohexane Monoterpenes
- Down-Regulation
- Genetic Variation
- Isoproterenol
- Kinetics
- Lymphoma
- Mathematics
