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Article

Gene expression profiling of canine osteosarcoma reveals genes associated with short and long survival times

1 Jan 2009

Abstract excerpt

BACKGROUND: Gene expression profiling of spontaneous tumors in the dog offers a unique translational opportunity to identify prognostic biomarkers and signaling pathways that are common to both canine and human. Osteosarcoma (OS) accounts for approximately 80% of all malignant bone tumors in the dog. Canine OS are highly comparable with their human counterpart with respect to histology, high metastatic rate and...

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PMID: 19735553
DOI: 10.1186/1476-4598-8-72

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