Article
Intracellular calcium deficits in Drosophila cholinergic neurons expressing wild type or FAD-mutant presenilin.
PloS one - 4 Sept 2009
Michno Kinga, Knight David, Campusano Jorge M, Campussano Jorge M, van de Hoef Diana, Boulianne Gabrielle L
Abstract excerpt
Much of our current understanding about neurodegenerative diseases can be attributed to the study of inherited forms of these disorders. For example, mutations in the presenilin 1 and 2 genes have been linked to early onset familial forms of Alzheimer's disease (FAD). Using the Drosophila central...
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