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Article

Gut mucosal cell damage in meningococcal sepsis in children: Relation with clinical outcome*

17 Dec 2009

Abstract excerpt

OBJECTIVE: The pathophysiological sequelae of meningococcal sepsis are mainly caused by deregulated microvasculature function, leading to impaired tissue blood flow. Because mature enterocytes are known to be susceptible to altered perfusion, we aimed to investigate: (1) the development of enterocyte damage; and (2) the relation between enterocyte damage and severity of disease and outcome in children with...

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PMID: 19730255
DOI: 10.1097/ccm.0b013e3181b4a5ed

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