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Antimicrobial Proteins and Peptides in Early Life: Ontogeny and Translational Opportunities

18 Aug 2016

Abstract excerpt

While developing adaptive immune responses, young infants are especially vulnerable to serious infections, including sepsis, meningitis, and pneumonia. Antimicrobial proteins and peptides (APPs) are key effectors that function as broad-spectrum anti-infectives. This review seeks to summarize the clinically relevant functional qualities of APPs and the increasing clinical trial evidence for their use to combat...

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PMID: 27588020
DOI: 10.3389/fimmu.2016.00309

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