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Article

Personalized medicine: genetic variation and loss of physiologic complexity are associated with mortality in 644 trauma patients.

Annals of surgery - 1 Oct 2009

Norris Patrick R, Canter Jeffrey A, Jenkins Judith M, Moore Jason H, Williams Anna E, Morris John A

Abstract excerpt

OBJECTIVE: Personalized medicine merges genetics, physiology, and patient outcome. Loss of physiologic complexity (heart rate [HR] variability) is a bedside biomarker for autonomic nervous system (ANS) dysfunction. We hypothesized that variability in ANS receptor proteins (genetics) and loss of c...

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Identifiers

PMID: 19730237
DOI: 10.1097/SLA.0b013e3181b8fb1f

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ADRB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19730237-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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