Article
Relationship between molecular markers and treatment response in a retrospective cohort of Indian patients with primary carcinoma of the larynx.
Oral oncology - 1 Dec 2009
Sahoo R, Chittibabu V, Patil G, Rao S, Thakur S, Dhondalay G, Kulkarni A J, Banerjee A, Ajaikumar B S, Korlimarla A, Nargund A, Niti R N, Gopinath K S, Prabhudesai Shilpa, Raghavendra R M
Abstract excerpt
p53 Mutations and over expression have been shown to predict treatment response in head and neck cancer patients. Failure of organ sparing therapy has been attributed to cisplatin and radiotherapy resistance in carcinoma of the larynx patients. In this study, we evaluate the relationships between p53 over expression/mutations, bcl(2) expression and ploidy status in a retrospective cohort of responder and...
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