Article
Stimulation of the human immunodeficiency virus type 2 (HIV-2) gene expression by the cytomegalovirus and HIV-2 transactivator gene.
AIDS research and human retroviruses - 1 May 1990
Arya S K, Sethi A
Abstract excerpt
Human immunodeficiency virus (HIV) often causes latent infection. Transactivation by some DNA viruses has been implicated in inducing HIV-1 replication and pathogenesis. The transactivator (IE-2) gene of the human cytomegalovirus (CMV) can enhance HIV-2 as well as HIV-1 gene expression in vitro....
Topics
- CD4-Positive T-Lymphocytes
- Cells, Cultured
- Cytomegalovirus
- Gene Expression Regulation, Viral
- Genes, Viral
- Genes, tat
- HIV-1
- HIV-2
- Humans
- Lymphocyte Activation
- Mutation
- Repetitive Sequences, Nucleic Acid
- Trans-Activators
- Transcription, Genetic
- Transcriptional Activation