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Article

p16INK4A, p53, EGFR expression and KRAS mutation status in squamous cell cancers of the anus: correlation with outcomes following chemo-radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Oct 2013

Gilbert Duncan C, Williams Anthony, Allan Kimberley, Stokoe Joanna, Jackson Tim, Linsdall Suzanne, Bailey Charles Mh, Summers Jeff

Abstract excerpt

BACKGROUND AND PURPOSE: Squamous cell carcinomas of the anal canal are associated with infection with Human Papilloma Viruses (HPVs). Chemo-radiotherapy (CRT) gives 70% 3-year relapse-free survival. Improved predictive markers and therapeutic options are required. METHODS: Tumours from 153 patients treated with radical chemo-radiotherapy (50.4 Gy in 28# with concurrent Mitomycin and 5-Fluorouracil between 2004...

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Share to Anus Neoplasms
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Cyclin-Dependent Kinase Inhibitor p16

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Source

Identifiers

PMID: 24021343
DOI: 10.1016/j.radonc.2013.08.002

Genes

KRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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