Article
['Migraine and a hole in the heart': causal relationship between migraine and patent foramen ovale not established].
Nederlands tijdschrift voor geneeskunde - 13 May 2006
Terwindt G M, Haan J, Bax J J, de Bruijn S F T M, Ferrari M D
Abstract excerpt
The relationship between patent foramen ovale (PFO) and migraine is controversial. A common genetic background seems possible, but there is no evidence for a causal relationship. Despite the lack of evidence, PFO closure is recommended in many countries as a remedy for migraine. At present, PFO closure for migraine should only be carried out under strictly controlled clinical trial conditions.
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