Article
AIF: not just an apoptosis-inducing factor.
Annals of the New York Academy of Sciences - 1 Aug 2009
Joza Nicholas, Pospisilik J Andrew, Hangen Emilie, Hanada Toshikatsu, Modjtahedi Nazanine, Penninger Josef M, Kroemer Guido
Abstract excerpt
Since its discovery nearly a decade ago, apoptosis-inducing factor (AIF) has had anything but a staid and uneventful existence. AIF was originally described as a mitochondrial intermembrane protein that, after apoptosis induction, can translocate to the nucleus and trigger chromatin condensation...
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