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Article

Apoptosis-inducing factor regulates skeletal muscle progenitor cell number and muscle phenotype.

PloS one - 1 Jan 2011

Armand Anne-Sophie, Laziz Iman, Djeghloul Dounia, Lécolle Sylvie, Bertrand Anne T, Biondi Olivier, De Windt Leon J, Chanoine Christophe

Abstract excerpt

Apoptosis Inducing Factor (AIF) is a highly conserved, ubiquitous flavoprotein localized in the mitochondrial intermembrane space. In vivo, AIF provides protection against neuronal and cardiomyocyte apoptosis induced by oxidative stress. Conversely in vitro, AIF has been demonstrated to have a pro-apoptotic role upon induction of the mitochondrial death pathway, once AIF translocates to the nucleus where it...

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Identifiers

PMID: 22076146
DOI: 10.1371/journal.pone.0027283
PMCID: PMC3208607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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