Article
Microbial-host interactions in inflammatory bowel diseases and experimental colitis.
Nestle Nutrition workshop series. Paediatric programme - 1 Jan 2009
Sartor R Balfour
Abstract excerpt
UNLABELLED: The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), are immunologically mediated with genetic and environmental influences. Genetic factors include defective immunoregulation, mucosal integrity/repair and bacterial killing. Commensal bacteria activate pathogenic bacterial antigen-specific effector T cells that cause chronic inflammation in genetically susceptible...
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