Article
Partial sequencing of recent Portuguese myxoma virus field isolates exhibits a high degree of genetic stability.
Veterinary microbiology - 6 Jan 2010
Muller A, Silva E, Abrantes J, Esteves P J, Ferreira P G, Carvalheira J C, Nowotny N, Thompson G
Abstract excerpt
To study genetic changes underlying myxoma virus evolution in its new host, the European rabbit (Oryctolagus cuniculus), we sequenced selected genomic regions of nine recent virulent field strains and a live attenuated vaccine strain ("MAV", Germany). DNA was extracted from cell culture passaged myxoma virus. A total of 4863 bp (approximately 3% of the genome) of 10 regions spanning 12 genes of the myxoma viruses...
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