Article
Genetic Variability of Myxoma Virus Genomes.
Journal of virology - 15 Feb 2017
Braun Christoph, Thürmer Andrea, Daniel Rolf, Schultz Anne-Kathrin, Bulla Ingo, Schirrmeier Horst, Mayer Dietmar, Neubert Andreas, Czerny Claus-Peter
Abstract excerpt
Myxomatosis is a recurrent problem on rabbit farms throughout Europe despite the success of vaccines. To identify gene variations of field and vaccine strains that may be responsible for changes in virulence, immunomodulation, and immunoprotection, the genomes of 6 myxoma virus (MYXV) strains were sequenced: German field isolates Munich-1, FLI-H, 2604, and 3207; vaccine strain MAV; and challenge strain ZA. The...
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