Article

MHC-I diversity enables rapid adaptation during viral pandemic in wild rabbit populations

2025-10-31

Abstract excerpt

Emerging diseases can have devastating consequences for wild species, with long-term effects depending on the ability of the host to evolve resistance. Here, we show that major histocompatibility complex (MHC) genes provided standing genetic variation that enabled rabbits to mount a rapid evolutionary response to the myxoma virus pandemic that began in the 1950s. Using historical and modern specimens starting in 1...

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Literature Corpus work: 8b40bfe3-7b6e-5f13-b74b-c640c68e80e3
DOI: 10.1101/2025.10.30.685367

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