Reconstitution of T-cell function after CD6-depleted allogeneic bone marrow transplantation.

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Article

Reconstitution of T-cell function after CD6-depleted allogeneic bone marrow transplantation.

Blood - 15 May 1990

Soiffer R J, Bosserman L, Murray C, Cochran K, Daley J, Ritz J

Abstract excerpt

Patients who undergo allogeneic bone marrow transplantation (BMT) are clinically immunodeficient for a prolonged period after engraftment. In the present study, we examined immune function after BMT in a series of patients who had received HLA compatible sibling marrow grafts purged of T cells with anti-CD6 monoclonal antibody and complement. None of the patients in this analysis received immunomodulating agents...

Topics

Adolescent
Adult
Antibodies, Monoclonal
Antigens, CD
Antigens, Differentiation, T-Lymphocyte
Bone Marrow
Bone Marrow Cells
Bone Marrow Transplantation
CD2 Antigens
Calcium
Cell Differentiation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Cell Division

Cells, Cultured

Humans

Interleukin-2

Leukocytes, Mononuclear

Lymphocyte Depletion

Middle Aged

Source

Open in PubMed

Identifiers

PMID: 1970938

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1970938-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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