Article
Natural killer (NK) and T cell-associated surface marker expression following allogeneic and autologous bone marrow transplantation (BMT).
Journal of hematotherapy & stem cell research - 1 Feb 2000
Nagler A, Rabinowitz R, Rosengolts-Rat J, Condiotti R, Schlesinger M
Abstract excerpt
Natural killer (NK) and T cell development was studied after allogeneic and autologous BMT. We determined the phenotypic expression and lytic ability of these subpopulations after BMT. Following T cell-depleted (TCD) BMT, the number of CD16+ and CD56+ cells peaked at 39 and 46 days, respectively, and constituted the majority of peripheral blood lymphocytes (PBL). Coexpression of CD3 and CD16 was <10% up to 14.5...
Topics
- Adolescent
- Adult
- Antigens, CD
- Bone Marrow Transplantation
- CD56 Antigen
- Child
- Child, Preschool
- Cytotoxicity, Immunologic
- Female
- Humans
- Killer Cells, Natural
- Lymphocyte Depletion
- Lymphocyte Subsets