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Article

Immunological reconstitution following bone marrow transplantation

1 Jun 1997

Abstract excerpt

The recipients of hematopoietic stem cell transplants are characterized by an immunodeficiency of varying severity and duration. Their immunoincompetence is due in part to: 1) a lack of sustained transfer of donor immunity, 2) a recapitulation of lymphoid ontogeny, 3) the effects of graft-versus-host disease and its therapy, and 4) a reduction in thymic function. Recipients can have delays in the production of...

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PMID: 9255623
DOI: 10.1111/j.1600-065x.1997.tb00975.x

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