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Article

Identification of a human cyclin D1-derived peptide that induces human cytotoxic CD4 T cells.

PloS one - 25 Aug 2009

Dao Tao, Korontsvit Tatyana, Zakhaleva Victoria, Haro Kurtis, Packin Jonathan, Scheinberg David A

Abstract excerpt

Cyclin D1 is over-expressed in various human tumors and therefore can be a potential oncogenic target antigen. However, only a limited number of T cell epitopes has been characterized. We aimed at identifying human cyclin D1-derived peptides that include both CD4 and CD8 T cell epitopes and to test if such multi-epitope peptides could yield improved cytotoxic CD8 T cell responses as well as cytotoxic CD4 T cells....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19707583
DOI: 10.1371/journal.pone.0006730
PMCID: PMC2726944

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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