Article
Gene polymorphism in transforming growth factor-beta codon 10 is associated with susceptibility to Giardiasis.
International journal of immunogenetics - 1 Dec 2009
Taherkhani H, Hajilooi M, Fallah M, Khyabanchi O, Haidari M
Abstract excerpt
Secretory immunoglobulin A (S-IgA) antibodies have a central role in anti-Giardial defence. It has been demonstrated that transforming growth factor-beta1 (TGF-beta1) stimulates B lymphocytes to produce and secrete S-IgA. We sought to determine the association between TGF-beta1 polymorphism (T+869C) with susceptibility to Giardiasis. The TGF-beta1 genotypes and levels of salivary (S-IgA) were analysed in...
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