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Article

Gene-specific changes in promoter occupancy by thyroid hormone receptor during frog metamorphosis. Implications for developmental gene regulation.

The Journal of biological chemistry - 16 Dec 2005

Buchholz Daniel R, Paul Bindu D, Shi Yun-Bo

Abstract excerpt

In all vertebrates, thyroid hormones (TH) affect postembryonic development. The role of the TH receptor (TR) in mediating the TH signal is complex as evidenced by divergent phenotypes in mice lacking TH compared with TR knock-out mice. We have proposed a dual function model for TR during development based on studies of frog metamorphosis. Here we examined an important assumption of this dual function model by...

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PMID: 16236718
DOI: 10.1074/jbc.M509593200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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